Research Areas
Genetics of Plant Biochemistry

Plants produce thousands of compounds that are essential not only for their own growth and development, but are also important for human nutrition, medicine, and many commercially important processes. A complete understanding of the biosynthesis and function of phytochemicals requires knowledge of the genes encoding the underlying biosynthetic enzymes, as well as proteins that regulate their action. Modern genetic technologies make it possible to identify mutations in plant genes that control sequential biochemical reactions. Such mutants are invaluable for dissecting the number and order of steps in a given metabolic pathway, as well as the physiological function of that pathway.

The genetics of plant biochemistry represents a research focus area within the Genetics Program at MSU. Ongoing research in several laboratories is aimed at elucidating the genetic basis of lipid metabolism, carbohydrate metabolism, carotenoid biosynthesis, cell wall formation, and the biosynthesis of compounds involved in plant defense. Major goals of this research include the identification of regulatory genes that control the flux of metabolites into specific biochemical pathways, and genetic manipulation of these genes for increased production of products of the pathways.

FACULTY NAME

RESEARCH DESCRIPTION

Christoph Benning biosynthesis and function of membrane lipids in photosynthetic organisms
Dean Della Penna genetics of cell wall synthesis and production of secondary metabolites
Gregg Howe biochemical basis of plant defense responses
Robert Last arabidopsis functional genomics; regulation of plant metabolic pathways for nutritionally important molecules; plant stress tolerance mechanisms; metabolic engineering of plants.
John Ohlrogge genetic control of plant lipid metabolism
Robert Larkin regulation of chlorophyll biosynthesis
Beronda Montgomery-Kaguri biosynthesis and function of biliprotein photoreceptors in photosynthetic organisms

Jack Preiss

genetics and metabolic regulation of glycogen and starch synthesis
Jonathan Walton biochemical basis of fungal-plant interactions
Andreas Weber genetic basis of intracellular transporters in plants