Research Areas
Genomics and Proteomics

Genomics and proteomics are just two of the terms used to describe the identification and characterization of set of genes, RNA, and proteins that comprise an organism. As exemplified by the Human Genome Project, the development of molecular maps, DNA chips and other high-throughput research tools have produced great advances and new insights for biology. With the help of these tools, it is now possible to understand how genotype leads to phenotype, how an organism responds to the environment, and other complex biological questions.

MSU scientists are leading a number of efforts for the development and the implementation of genomic tools in human, plant, animal and microbial species. Although the organisms under study are diverse, the application of common approaches forms natural ties that unify the research groups and promotes comparative genomics.

FACULTY NAME

RESEARCH DESCRIPTION
Andrea Amalfitano utilizing array based technologies to evaluate the impact that various gene transfer modalities have upon mammalian cells and/or living animals
Christoph Benning functional genomics of Arabidopsis and photosynthetic bacteria.
Robert Britton genomics of Bacillus subtilus, genomics of probiotic/pathogen interactions.
Christina Chan apply system biology approaches to reconstruct signaling and gene regulatory pathways to help elucidate disease mechanisms and identify pharmaceutical targets
Hans Cheng structural and functional genomics of disease resistance in chicken.
Todd Ciche comparative genomics of symbiosis, parasitism and sex determination of nematodes
Dean Della Penna functional genomics of plants to accomplish nutritional improvement
Jerry Dodgson chicken genome mapping and transgenic poultry.
Catherine Ernst genomics of growth in pigs and cattle, mammalian comparative genome mapping
Kyung-Hwan Han genomics of secondary growth in plants for metabolic engineering
Gregg Howe genomics of plant-insect interactions
Jianping Hu use genomic approaches to discover genes involved in the communication between peroxisomes and other organelles
Ning Jiang computational identification of transposable elements, the impact of transposable elements on gene expression and gene function, using a combination of bioinformatics and experimental approaches
Kenneth Keegstra novel gene discovery in plants through a genomic approach
Lee Kroos genomic assessment of bacterial development
John LaPres functional and toxigenomic approaches to understanding the toxicity of environmental pollutants
Robert Last arabidopsis functional genomics; regulation of plant metabolic pathways for nutritionally important molecules; plant stress tolerance mechanisms; metabolic engineering of plants.
Laura McCabe genomic and proteomic approches to identify genes involved in regulating bone formation under conditions of spaceflight, limb disuse and disease states.
J. Justin McCormick genomic approaches for understanding carcinogenesis.
John Ohlrogge genomics for genetic engineering of plant oils
Katherine Osteryoung chloroplast proteomics
Jack Preiss genomics of of glycogen and starch biosynthesis.
Tao Sang genetics of adaptation
Thomas Schmidt genomic approaches to microbial ecology
Mariam Sticklen production of biobased industrial material in crops via cell and molecular biology.
George Sundin genomics of plant-bacterial interactions
Robert Tempelman design and hierarchical linear statistical model analysis of gene expression microarray experiments
Frances Trail genomic analysis to identify genes important in fungal growth and development, with particular emphasis on sexual reproduction and sporulation
Bruce Uhal Lung epithelial stem cell function; regulation of epithelial cell death (apoptosis); molecular mechanisms of lung fibrogenesis and repair.
Patrick Venta canine genome mapping and genomics for studying inherited disorders
Dechun Wang soybean breeding and genetics in disease and insect resistance, seed quality and agronomic performance
Thomas Whittam genomics for assessment of pathogenic bacteria and emerging infectious diseases
Peter Wolk genomic assessment of cyanobacterial developmental programs
Vincent Young campylobacter and helicobacter, animal models of infectious diseases, gastrointestinal microbiology/ecology
Tim Zacharewski functional genomics for studies of toxicology and endocrine disruption in human and wildlife models.