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  CMB Faculty:
Signal Transduction
 

Christina Chan (Ph.D., Univ. of Pennslyvania), CHEMICAL ENGINEERING & MATERIALS SCIENCE - Signal transduction and crosstalk between apoptosis and insulin signaling, i.e. PKR signaling; identifying patheays for drug targets in liver diseases,Aalzhiemer's disease and cancer using experimental and computational techniques.

Alex Chen
(Ph.D., Southern Illinois), PHARMACOLOGY & TOXICOLOGY - Cell and molecular vascular biology and disease, including cell- and gene-based therapies of vascular dysfunction in rodent models of human hypertension and diabetes.

Kate J. Claycombe (Ph.D., Univ. of Tennessee), FOOD SCIENCE & HUMAN NUTRITION/NUTRITIONAL IMMUNOLOGY - Effects of nutrients on immune dysfunction in Type II diabetes.

Susan E. Conrad (Ph.D., Caltech), MICROBIOLOGY & MOLECULAR GENETICS - Control of the mammalian cell cycle; estrogen regulation of breast cancer cell proliferation.

David DeWitt (Ph.D. Michigan State), BIOCHEMISTRY & MOLECULAR BIOLOGY - Molecular and cellular biology of lipid signaling by prostaglandins.

Walter J. Esselman (Ph.D., Penn State), MICROBIOLOGY & MOLECULAR GENETICS - The expression and function of lymphocyte CD45 protein tyrosine phospatase in the regulation of signaling, the cell cycle, and transformation.

Michele M. Fluck (Ph.D., Geneva), MICROBIOLOGY & MOLECULAR GENETICS - Viral Oncology; oncogene activation of transcription factors and their effect on chromatin structure and DNA replication; mammary gland oncogenesis in mice and dependence upon estrogen.

James J. Galligan (Ph.D., Arizona), PHARMACOLOGY & TOXICOLOGY - Neural control of gastronintestinal (GI) motility and blood flow; neural control of arteries and veins; hypertension.

Kathleen A. Gallo (Ph.D., Harvard), PHYSIOLOGY AND BIOCHEMISTRY & MOLECULAR BIOLOGY - We are studying the role of SPRK and of other novel protein kinases in mammalian signal transduction and cancer.

Patricia E. Ganey - (Ph.D., Michigan State), PHARMACOLOGY AND TOXICOLOGY - Mechanisms of liver injury; role of phagocytic cells in hepatotoxicity.

Lee Kroos (Ph.D., Stanford), BIOCHEMISTRY & MOLECULAR BIOLOGY - Regulation of gene expression during development; prokaryotic RNA polymerases and regulatory proteins; Bacillus sporulation; cell-cell interactions in Myxococcus.

Richard J. Miksicek (Ph.D., University of Minnesota), PHYSIOLOGY - Molecular endocrinology and breast cancer; steroid hormone receptors; gene expression.

L. Karl Olson (Ph.D., Minnesota), PHYSIOLOGY - Molecular endocrinology; regulation of pancreatic beta cell gene expression.

Shin-Han Shiu (Ph.D., Univ. of Wisconsin-Madison), PLANT BIOLOGY - Evolution of duplicate genes; identifying novel genes and novel cis-regulatory elements.

William Smith (Ph.D., Michigan), BIOCHEMISTRY & MOLECULAR BIOLOGY - Prostaglandin biochemistry and endocrinology; G protein-linked receptors.

Bill Spielman (Ph.D. Missouri), PHYSIOLOGY - Cellular renal physiology; G-protein-linked receptors; adenosine receptors.

Bruce D. Uhal (Ph.D. Saint Louis University), PHYSIOLOGY -Regulation of epithelial cell proliferation and death; role of local angiotensin systems in signaling of apoptosis.

Hongbing Wang (Ph.D., UCLA), NEUROSCIENCE - Cyclic AMP signaling and neuroplasticity.

Chengfeng Yang (Ph.D., Singapore), PHYSIOLOGY & VETERINARY MEDICINE - Growth factors and hormones-mediated tyrosine kinase and the small Rho GTPase signaling in cancer development and progression.


© 2003 College of Natural Science Cell and Molecular Biology
Michigan State University